That's important because the health of most tissues hinges, in large part, on blood flow and nutrients, Horowitz said. When we gain weight, our fat cells expand, but if blood flow to fat tissue doesn't increase in parallel, it could become unhealthy or even necrotic. Horowitz stressed that the two studies are relevant mainly to obese people at risk for metabolic disease. However, there's a takeaway here for everyone. "We believe that the regular exercise we do now may create a healthier fat-storing environment for those times when we do overeat and gain weight," Horowitz said. Taken together, the studies also support the notion that clinicians must redefine their view of fat, said Horowitz. "Adipose tissue is scorned because most people see it as causing disease and obesity, but in general adipose tissue doesn't cause people to gain weight and become obese, it's just where we store our extra energy when we do overeat," Horowitz said. "Our studies aren't suggesting it is healthy to be obese or to overeat -- but when we do overeat, it is important to have a safe place to store that extra energy,Having a is advantageous in vape cartridge packaging as it's healthier. Ceramic parts are resistant to abrasion and oxidation unlike other alloy wires where, oxidation occurs at higher temperature. "When people gain the same amount of body fat, those with adaptations to their fat tissue that can more healthfully accommodate the extra fat may be protected from developing insulin resistance and obesity-related diseases. We have identified some of these adaptations." Doug Van Pelt, a former doctoral student in the Horowitz lab, conducted this work as part of his dissertation. Van Pelt is currently a postdoctoral fellow at the University of Kentucky's College of Health Sciences. The two studies are: "Factors regulating subcutaneous adipose tissue storage, fibrosis, and inflammation may underlie low fatty acid mobilization in insulin-sensitive obese adults" and "Aerobic exercise elevates markers of angiogenesis and macrophage IL6 gene expression in the subcutaneous adipose tissue of overweight to obese adults."