Orchitis often occurs in conjunction with mumps. It is usually the belief that mumps with orchitis is rare before puberty, so there is certainly less risk of permanent injury to the testis, even when it's involved, it could usually fully cured. People with mumps after adolescence are more inclined to are afflicted by orchitis, when they get mumps, they need to focus on enough rest and timely treatment to stop the occurrence of orchitis. So how come mumps patients at risk of orchitis? In fact, among the characteristics in the mumps virus is that it not just acts on glands and also on nerve tissue, pancreas, especially testis. Patients with orchitis landed 1/5-1/4 in the patients with mumps. Postpubertal orchitis can result in irreparable damage of testicular seminiferous duct epithelial cells and interstitial cells by virus and will cause testicular atrophy in some severe cases. In addition, bilateral mumps orchitis in men can also cause hypogonadism, sometimes they will also be together with azoospermia or even a severe decline in sperm count, that is below 4 million/ml. Diagnosis of orchitis just isn't tough to establish, like testicular discomfort and pain, with very sensitive and intense tenderness, plus unilateral or bilateral testicular swelling, symptoms, and signs are normal. Of course, before or concurrently, you can find often symptoms and signs of mumps. Sometimes patients may only have signed on the one hand of the testicles, but that doesn't mean the contralateral testicles are not involved. Degenerative lesions can nonetheless be noticed in both testicles. When the structure of testicular cells is destroyed and fibrosis occurs, not merely spermatogenic epithelial cells and also interstitial cells could happen. In severe cases, Sertoli cell-only syndrome may be confirmed inside a testicular biopsy, that is, no spermatogenic cells appear in the seminiferous tubule in the patient. Some patients still have progressive fibrosis of testis in many years following the disease. Even if the patient still has spermatogenesis, the count might be inside normal range, though the sperm motility rate is often no more than 30%, as well as the speed of movement is significantly reduced. Because with the different causes of mumps and orchitis, the treatment in pre-adolescent boys is mainly centered on mumps itself. For post-adolescent men, the treatment is principally targeting orchitis. Supportive therapy includes enough rest, prompt treatment, careful nursing, placement of cold water bags in the testis which may alleviate patients’ pain and discomforts, and also the utilization of T-bands supports the scrotum to ease symptoms (pain and swelling) to be able to prevent reducing the occurrence of sequelae. Especially for patients who have severe testicular pain, the timely using adequate anti-inflammatory drugs and analgesics is needed. In fact, patients could also select the conservative natural medicine Dr. Lee Diuretic and Anti-inflammatory Pill for treatment. The prescription contains many natural medicines, for example Aconitum, Safflower, Peach kernel, Angelica Sinensis, Radix Paeoniae Rubra, cordate houttuynia, cowherb seed and etc. Unlike these drugs, it will not produce unwanted side effects, so patients will take it for a long period. At the same time, the efficacy of bactericidal and anti-inflammation, clearing away heat and detoxification, activating blood circulation and removing blood stasis, promoting diuresis and relieving stranguria can completely take away the inflammation in the testicles and avoid recurrence.