Testicular disease is often caused by trauma, inflammation, tumor and so on. Testicular disease affects the normal operation of the reproductive system. It can lead to male infertility, so testicular pain should be timely treatment, if patient delay treatment time, it is not only pain in the body but also hurt in the heart. Which inflammation causes the pain of the testicles? 1.it is the most common disease that causes testicular pain in men: Orchitis is caused by inflammation of the testis. Most of the cases are caused by the deterioration of testicular diseases. The stimulation of inflammation causes testicular pain. The presence of orchitis can seriously damage the testicular function of men, so that testicular makes sperm in decline, if it is not treated in time, it will cause male’s infertility. 2. It is a reason that causes testicular pain: The male’s epididymis is close to the testicles. If it has infected inflammation, the inflammation will spreads to the testicles. like orchitis, It is stimulates the testis and causes testicular pain in males. Epididymitis can also damage testicles resulting in male infertility. 3.It is also the reason that causes male’s testicular pain: Scrotum is responsible for the growth and development of spermatozoa and it is responsible for temporarily store sperm. The scrotal inflammation not only stimulates the male’s testicles, but also damages the sperm in the seminal vesicle and causes the death of the sperm, thus reducing the male fertility and causing male infertility. 4.Other inflammatory diseases. The other inflammations also cause pain in testis. For example, prostatitis, male endocrine disorders, urethral infections and so on.