Male genital organs are more complex, but they are generally classified into two reproductive organs, internal and external. The external genitals include the scrotum and the penis; the internal genitals include the testis and the spermatic duct (epididymis, vas deferens, ejaculatory tube, and urethra) and the glands, seminal vesicles, prostate, and urethral glands. Normal males develop sexual organs at puberty and begin to secrete androgens and sperm, as well as fertility. The health of male reproductive organs determines the strength of fertility. Then, when a man has orchitis, will their fertility be affected? The male testis is responsible for the secretion of sex hormones and the production of part of the seminal plasma and the storage of sperm throughout the reproductive organs. The main component of the sex hormone is testosterone, it has the role of maintaining spermatogenesis. Testosterone is secreted from stromal cells and can enter the seminiferous tubules by supporting cells. it can be directly or first converted to more active dihydrotestosterone, combined with androgen receptor of spermatogenic cells to promote sperm production. When testitis occurs, inflammatory bacteria or viruses kill normal cells in the dormitory testis and replace them with pathogenic cells. This is very harmful to the survival, quality and quantity of sperm, and may lead to oligozoospermia, azoospermia or sperm death. At the same time, orchitis can cause a man's testicular pain, redness and fever, which may cause impotence, premature ejaculation, erectile difficulty, loss of sexual desire, can not ejaculation, or even sexual life. All this hinders the formation and ejection of sperm. All of these conditions may directly or indirectly affect male fertility, reduce the risk of conception, or cause lifelong infertility. However, infertility caused by inflammation of the genital organs such as orchitis can be improved or even cured by drugs. Patients should not be overloaded with heavy mental stress, and should not miss the best time to treat.